If you are coming by car from the south, take the A22 motorway and exit at Chiusa/Val Gardena. From here, follow the main road towards Val Gardena, and continue over the Passo Gardena until you reach Colfosco.
If you are coming from the north, take the A22 motorway and exit at Bressanone, follow the main road SS49 until you reach the crossroad of S. Lorenzo. From here continue along the SS244 until you reach Colfosco after approximately 40 km.
If you are travelling by train, get off at the station in Bolzano, Ponte Gardena, Bressanone or Brunico. From there, there are regularly public buses to Colfosco.